Juvenile idiopathic arthritis genetics - what's new? What's next?
Thomson W, Donn RP
Arthritis Res. 2002;4, 5:302-306.
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Studies have established the magnitude of the genetic basis of juvenile idiopathic arthritis (JIA). JIA is a complex genetic condition and the genes that influence susceptibility are actively being sought. A candidate gene approach is being used by several groups. MHC-, cytokine- and T-cell-related genes have all been positively associated with JIA. Here we review some of the latest genetic data, and discuss ways in which JIA genetic research might proceed
Arthritis; Arthritis,Juvenile Rheumatoid; Child; Child,Preschool; Epidemiology,Molecular; Gene Expression Profiling; Genetic Predisposition to Disease; Genotype; Human; International Cooperation; Research; World Health; epidemiology; genetics; immunology