Related resources
Search for item elsewhere
University researcher(s)
Academic department(s)
The rhodopsin-encoding gene of bony fish lacks introns.
Fitzgibbon J, Hope A, Slobodyanyuk S, Bellingham J, Bowmaker J, Hunt D
Gene. 1995;164( 2):273-7.
Access to files
Full-text and supplementary files are not available from Manchester eScholar. Use our list of Related resources to find this item elsewhere. Alternatively, request a copy from the Library's Document supply service.
Abstract
A study of the sequences of the rhodopsin-encoding genes (Rh) in eight fish species from two of the major subdivisions of the teleosts reveals that no introns are present in the coding region. This contrasts with the opsin-encoding genes of all other vertebrates where either four or five introns are invariably found. Phylogenetic analysis shows that this intronless teleost Rh is homologous to the intron-containing Rh of amphibia, birds and mammals. Possible mechanisms for intron loss are discussed, including replacement by homologous conversion of Rh with a processed cDNA.
Keyword(s)
Animals; Base Sequence; Cattle; Chickens; DNA Primers; Humans; Introns; Mice; Molecular Sequence Data; Phylogeny; Polymerase Chain Reaction; Sequence Homology, Nucleic Acid; Species Specificity; Variation (Genetics); genetics: Amphibia; genetics: Anguilla; genetics: Birds; genetics: Decapodiformes; genetics: Drosophila; genetics: Fishes; genetics: Goldfish; genetics: Mammals; genetics: Rhodopsin; genetics: Vertebrates; genetics: Xenopus