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Exacerbation of atopic dermatitis after bacillus Calmette-Guérin vaccination.

Dalton, S J; Haeney, M R; Patel, L; David, T J

Journal of the Royal Society of Medicine. 1998;91(3):133-134.

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In two children with atopic dermatitis, routine vaccination with bacillus Calmette-Guérin (BCG) was followed by severe exacerbation of skin disease. If the sequence is cause and effect, a possible mechanism is stimulation of a Th2 lymphocyte cytokine profile by the vaccine, with migration of activated lymphocytes to inflamed skin. In children with active atopic dermatitis, BCG vaccination is best deferred until remission.

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Created by:
Ganeshwaran, Nilani
7th January, 2011, 13:59:37
Last modified by:
David, Timothy
Last modified:
4th February, 2016, 19:54:20

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